In this chapter, the author reflects on theorizations that have emerged in the last decades in different regions of Latin America around the concepts of “Buen Vivir” or “Vida Digna” based on conceptualizations developed by indigenous intellectuals, but which are based on epistemologies from the Mesoamerican or Andean region and which have given meaning to the daily lives of the original peoples. The chapter also analyzes the backward context that is currently being experienced in the Latin American continent regarding the recognition of the rights of indigenous peoples and the appropriation of these discourses by the so-called plurinational states, stripping them of their critical radicalism. Finally, the author takes a look at the way in which these conceptualizations are being vindicated by indigenous women from different regions of the continent to question gender violence and state violence that threatens the dignity of life and destabilizes the integrality of community relations.